SCHEMBL7864531

SCHEMBL7864531

CCCCCC(CCCCC(C)C)OC(=O)c1ccc(C(=O)O)cc1

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RARB P10826 5/20 0.51
TSHR P16473 2/20 0.47
MAPK1 P28482 1/20 0.47
TP53 P04637 1/20 0.47
ALDH1A1 P00352 1/20 0.46
PNLIP P16233 2/20 0.46
PLA2G4B P0C869 2/20 0.46
MAPT P10636 1/20 0.46
PRKCA P17252 1/20 0.44
PRKCD Q05655 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7864542 0.99 RARB (0.50) RARBTSHRMAPK1TP53ALDH1A1
SCHEMBL7866970 0.99 RARB (0.50) RARBTSHRMAPK1TP53ALDH1A1
SCHEMBL6672236 0.99 RARB (0.50) RARBTSHRMAPK1TP53ALDH1A1
SCHEMBL5371346 0.99 RARB (0.50) RARBTSHRMAPK1TP53ALDH1A1
SCHEMBL6671767 0.99 RARB (0.50) RARBTSHRMAPK1TP53ALDH1A1
SCHEMBL6670588 0.99 RARB (0.50) RARBTSHRMAPK1TP53ALDH1A1
SCHEMBL7859268 0.97 RARB (0.51) RARBTSHRMAPK1TP53ALDH1A1
SCHEMBL6673230 0.96 RARB (0.47) RARBTSHRMAPK1TP53ALDH1A1
SCHEMBL18485496 0.96 RARB (0.50) RARBTSHRMAPK1TP53ALDH1A1
SCHEMBL5371350 0.96 RARB (0.50) RARBTSHRMAPK1TP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0811639-B1 SOLID CATALYTIC COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST TOHO TITANIUM CO LTD (JP) 2001-08-01 EP disclosed
US-5965478-A A POLYMERIZATION CATALYST IS A REACTION PRODUCT OF A TITANIUM HALIDE, A DIESTER OF AROMATIC DICARBOXYLIC ACID AND A DIALKOXYMAGNESIUM PARTICLES HAVING A HIGH BULK DENSITY; POLYOLEFIN HAVING A HIGH STEREOREGULARITY, HIGH BULK DENSITY TOHO TITANIUM CO., LTD. (JP) 1999-10-12 US disclosed
EP-0811639-A1 SOLID CATALYTIC COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST TOHO TITANIUM CO., LTD. (JP) 1997-12-10 EP disclosed