Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 4/20 | 0.35 |
| ▸ | FNTA | P49354 | 2/20 | 0.34 |
| ▸ | FNTB | P49356 | 2/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563006 | 0.88 | FNTA (0.46) | CAPN1NAMPTFNTAFNTB | |
| SCHEMBL7864931 | 0.83 | FNTA (0.38) | CAPN1NAMPTFNTAFNTB | |
| SCHEMBL7563903 | 0.81 | NAMPT (0.40) | CAPN1NAMPTPGGT1B | |
| SCHEMBL7565309 | 0.80 | NAMPT (0.40) | CAPN1NAMPTPGGT1B | |
| SCHEMBL7565362 | 0.75 | FNTA (0.38) | FNTAFNTBPGGT1BMAPK1 | |
| SCHEMBL7563326 | 0.74 | FNTA (0.52) | FNTAFNTB | |
| SCHEMBL7570953 | 0.70 | FNTA (0.41) | FNTAFNTBMAPK1 | |
| SCHEMBL7563012 | 0.69 | FNTA (0.44) | NAMPTFNTAFNTB | |
| SCHEMBL7862157 | 0.68 | FNTA (0.51) | FNTAFNTBPGGT1B | |
| SCHEMBL7564340 | 0.67 | NAMPT (0.36) | CAPN1NAMPTFNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025088-B1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | ASTRAZENECA AB (SE) | 2001-09-05 | — | — | EP | disclosed |