Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563012 | 0.84 | FNTA (0.44) | NAMPT | |
| SCHEMBL7563910 | 0.82 | NAMPT (0.43) | NAMPT | |
| SCHEMBL7565317 | 0.81 | NAMPT (0.44) | NAMPT | |
| SCHEMBL7565371 | 0.78 | NAMPT (0.35) | NAMPT | |
| SCHEMBL7867257 | 0.72 | NAMPT (0.31) | NAMPT | |
| SCHEMBL7563333 | 0.71 | FNTA (0.50) | — | |
| SCHEMBL7564350 | 0.69 | NAMPT (0.41) | NAMPT | |
| SCHEMBL8193354 | 0.68 | FNTA (0.39) | — | |
| SCHEMBL7867264 | 0.67 | — | — | |
| SCHEMBL7563006 | 0.67 | FNTA (0.46) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025088-B1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | ASTRAZENECA AB (SE) | 2001-09-05 | — | — | EP | disclosed |