Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 19/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1263310 | 0.77 | HDAC6 (0.54) | HDAC6HDAC8HDAC3HDAC1HDAC7 | |
| SCHEMBL7868699 | 0.74 | HDAC6 (0.61) | HDAC6HDAC8HDAC3HDAC1 | |
| SCHEMBL12883241 | 0.72 | HDAC6 (0.53) | HDAC6HDAC8HDAC3HDAC1 | |
| SCHEMBL12210615 | 0.69 | HDAC6 (1.00) | HDAC6HDAC8HDAC3HDAC1HDAC7 | |
| SCHEMBL1173979 | 0.67 | HDAC6 (0.66) | HDAC6HDAC8HDAC3HDAC1 | |
| SCHEMBL12210633 | 0.67 | HDAC6 (0.88) | HDAC6HDAC8HDAC3HDAC1HDAC7 | |
| SCHEMBL12895868 | 0.66 | HDAC6 (0.58) | HDAC6HDAC8HDAC3HDAC1HDAC7 | |
| SCHEMBL7795811 | 0.65 | POLB (0.40) | HDAC6HDAC8HDAC1HSP90AA1 | |
| SCHEMBL1173867 | 0.65 | HDAC6 (0.66) | HDAC6HDAC8HDAC3HDAC1HSP90AA1 | |
| SCHEMBL1263733 | 0.64 | HDAC6 (1.00) | HDAC6HDAC8HDAC3HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151318-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-12-29 | — | — | WO | disclosed |