Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.63 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.46 |
| ▸ | ME2 | P23368 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26136026 | 0.86 | PDE4B (0.56) | BACE1PDE4BPTPN1 | |
| SCHEMBL28457253 | 0.84 | PDE4B (0.58) | BACE1PDE4BPTPN1MAPTKMT2A | |
| SCHEMBL7865883 | 0.79 | BACE1 (0.71) | BACE1PDE4BPTPN1MAPTMEN1 | |
| SCHEMBL29013073 | 0.79 | BACE1 (0.71) | BACE1PDE4BPTPN1MAPTMEN1 | |
| SCHEMBL16735432 | 0.78 | BACE1 (0.57) | BACE1PDE4BPTPN1MAPTALDH1A1 | |
| Triphenylene SCHEMBL16735423 | 0.78 | PDE4B (0.53) | BACE1PDE4BPTPN1MAPTKMT2A | |
| Water SCHEMBL20211702 | 0.77 | BACE1 (0.55) | BACE1PDE4BPTPN1MAPTALDH1A1 | |
| SCHEMBL13141855 | 0.77 | BACE1 (0.62) | BACE1PDE4BPTPN1MAPTMEN1 | |
| SCHEMBL9723700 | 0.77 | BACE1 (0.62) | BACE1PDE4BPTPN1MAPTMEN1 | |
| SCHEMBL28703417 | 0.76 | CYP3A4 (0.54) | BACE1PDE4BPTPN1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303733-B1 | FROM BISPHENOL COMPOUNDS AND DIFLUORO DIARYLACETYLENES AND/OR ETHYNYLATED BENZOPHENONES; DIELECTRICS EMPLOYED WITH A VARIETY OF MICROELECTRONIC DEVICES, FOR EXAMPLE, INTEGRATED CIRCUITS AND MULTICHIP MODULES. | ALLIEDSIGNAL INC. | 2001-10-16 | — | — | US | disclosed |