Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.63 |
| ▸ | HTR2C | P28335 | 1/20 | 0.63 |
| ▸ | HTR2B | P41595 | 1/20 | 0.63 |
| ▸ | KDM1A | O60341 | 19/20 | 0.58 |
| ▸ | KDM1B | Q8NB78 | 4/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.58 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7092720 | 1.00 | HTR2A (0.63) | HTR2AHTR2CHTR2BKDM1AKDM1B | |
| SCHEMBL7092719 | 1.00 | HTR2A (0.63) | HTR2AHTR2CHTR2BKDM1AKDM1B | |
| SCHEMBL14900233 | 0.85 | KDM1A (0.62) | HTR2AHTR2CHTR2BKDM1AKDM1B | |
| SCHEMBL16802361 | 0.85 | KDM1A (0.62) | HTR2AHTR2CHTR2BKDM1AKDM1B | |
| SCHEMBL6997477 | 0.82 | HTR2A (0.59) | HTR2AHTR2CHTR2BKDM1AKDM1B | |
| SCHEMBL3609223 | 0.82 | KDM1A (0.69) | HTR2AHTR2CHTR2BKDM1AKDM1B | |
| SCHEMBL12971950 | 0.82 | HTR2A (0.59) | HTR2AHTR2CHTR2BKDM1AKDM1B | |
| SCHEMBL15011508 | 0.82 | KDM1A (0.69) | HTR2AHTR2CHTR2BKDM1AKDM1B | |
| SCHEMBL15286633 | 0.82 | KDM1A (0.69) | HTR2AHTR2CHTR2BKDM1AKDM1B | |
| SCHEMBL6997479 | 0.82 | HTR2A (0.59) | HTR2AHTR2CHTR2BKDM1AKDM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251910-B1 | 1,2,3-triazolo[4,5-d]pyrimidines as P2T receptor antagonists | ASTRAZENECA UK LIMITED (GB) | 2001-06-26 | — | — | US | disclosed |