Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57132 | 0.98 | IDO1 (0.50) | IDO1PDPK1SLC18A3CYP11B2GRIN1 | |
| SCHEMBL29544390 | 0.98 | IDO1 (0.50) | IDO1PDPK1SLC18A3CYP11B2GRIN1 | |
| SCHEMBL21114381 | 0.98 | IDO1 (0.50) | IDO1PDPK1SLC18A3CYP11B2GRIN1 | |
| SCHEMBL3418678 | 0.98 | IDO1 (0.50) | IDO1PDPK1SLC18A3CYP11B2GRIN1 | |
| SCHEMBL1355960 | 0.98 | IDO1 (0.50) | IDO1PDPK1SLC18A3CYP11B2GRIN1 | |
| SCHEMBL29457637 | 0.98 | IDO1 (0.50) | IDO1PDPK1SLC18A3CYP11B2GRIN1 | |
| Ammonia Solution, Strong SCHEMBL6419944 | 0.95 | IDO1 (0.48) | IDO1PDPK1SLC18A3CYP11B2GRIN1 | |
| Hydrochloric Acid SCHEMBL3940929 | 0.95 | IDO1 (0.52) | IDO1PDPK1SLC18A3CYP11B2GRIN1 | |
| Ethane SCHEMBL9474214 | 0.93 | PDPK1 (0.52) | IDO1PDPK1SLC18A3CYP11B2GRIN1 | |
| Methylamine SCHEMBL6994455 | 0.91 | IDO1 (0.50) | IDO1PDPK1SLC18A3CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1067932-A4 | METHODS FOR INHIBITING MRP1 | LILLY CO ELI (US) | 2001-11-14 | — | — | EP | disclosed |
| EP-1067932-A1 | METHODS FOR INHIBITING MRP1 | ELI LILLY AND COMPANY (US) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999051236-A1 | METHODS FOR INHIBITING MRP1 | ELI LILLY AND COMPANY (US) | 1999-10-14 | — | — | WO | disclosed |