Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 16/20 | 0.55 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3757911 | 0.92 | PIK3CA (0.61) | PIK3CAPRKDC | |
| SCHEMBL13054200 | 0.87 | PIK3CA (0.60) | PIK3CAPRKDC | |
| SCHEMBL3756702 | 0.85 | PIK3CA (0.62) | PIK3CAPRKDCCREBBP | |
| SCHEMBL3750839 | 0.84 | PIK3CA (0.62) | PIK3CAPRKDCCREBBPGPR142 | |
| SCHEMBL3762172 | 0.83 | PIK3CA (0.60) | PIK3CAPRKDC | |
| SCHEMBL3749693 | 0.83 | PIK3CA (0.60) | PIK3CAPRKDC | |
| SCHEMBL3753243 | 0.83 | PIK3CA (0.60) | PIK3CAPRKDC | |
| SCHEMBL3754069 | 0.82 | PIK3CA (0.72) | PIK3CA | |
| SCHEMBL3747696 | 0.82 | PIK3CA (0.59) | PIK3CAPRKDC | |
| SCHEMBL13054109 | 0.79 | PIK3CA (0.59) | PIK3CAPRKDCCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118208-A1 | BENZOXAZEPIN-4- (5H) -YL DERIVATIVES AND THEIR USE TO TREAT CANCER | EXELIXIS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |