SCHEMBL78668

SCHEMBL78668

C=CC(O)(O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9344912 0.74
SCHEMBL1705892 0.74
SCHEMBL10828748 0.70
SCHEMBL11032703 0.70
SCHEMBL129187 0.70
SCHEMBL11397714 0.70
SCHEMBL10840834 0.70
SCHEMBL16970133 0.70
SCHEMBL8517556 0.70
SCHEMBL7166042 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10683327-B2 Compounds, linker-drugs and ligand-drug conjugates INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2020-06-16 US claimed
US-10618935-B2 Antibody-drug conjugate (ADC) and method for forming the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2020-04-14 US claimed
US-20190106459-A1 COMPOUNDS, LINKER-DRUGS AND LIGAND-DRUG CONJUGATES INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2019-04-11 US claimed
US-10233212-B2 Compounds, linker-drugs and ligand-drug conjugates INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2019-03-19 US claimed
EP-3165237-B1 ANTIBODY-DRUG CONJUGATE (ADC) AND METHOD FOR FORMING THE SAME IND TECH RES INST (TW) 2018-12-19 EP claimed
EP-3165532-B1 AURISTATIN DERIVATIVES, LINKER-DRUGS AND LIGAND-DRUG CONJUGATES IND TECH RES INST (TW) 2018-12-19 EP claimed
US-20180016300-A1 COMPOUNDS, LINKER-DRUGS AND LIGAND-DRUG CONJUGATES INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2018-01-18 US claimed
CN-107043406-A Compound, linker-drug, and ligand-drug conjugate 财团法人工业技术研究院 2017-08-15 CN claimed
CN-107029242-A Antibody drug complex and method for producing same 财团法人工业技术研究院 2017-08-11 CN claimed
EP-3165532-A2 AURISTATIN DERIVATIVES, LINKER-DRUGS AND LIGAND-DRUG CONJUGATES Industrial Technology Research Institute (TW) 2017-05-10 EP claimed
EP-3165237-A1 ANTIBODY-DRUG CONJUGATE (ADC) AND METHOD FOR FORMING THE SAME Industrial Technology Research Institute (TW) 2017-05-10 EP claimed
US-20170119902-A1 ANTIBODY-DRUG CONJUGATE (ADC) AND METHOD FOR FORMING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2017-05-04 US claimed
CN-102060952-B Styrene-acrylate emulsion with hydrophobic oleophylic fluorine-silicon-modified nuclear shell structure and preparation method thereof UNIV SOUTH CHINA TECH 2013-02-13 CN claimed
CN-102060952-A Styrene-acrylate emulsion with hydrophobic oleophylic fluorine-silicon-modified nuclear shell structure and preparation method thereof UNIV SOUTH CHINA TECH 2011-05-18 CN claimed
US-5496910-A BIODEGRADABLE THE DOW CHEMICAL COMPANY (US) 1996-03-05 US claimed
WO-1994005709-A1 THERMOPLASTIC POLYESTER LOW PROFILE ADDITIVES FOR VINYL ESTER/POLYESTER RESINOUS COMPOSITIONS ASHLAND OIL, INC. (US) 1994-03-17 WO claimed
US-5254642-A Shrinkage control ASHLAND OIL, INC. (US) 1993-10-19 US claimed
US-5116917-A Thermoplastic polyester low profile additives for vinyl ester resinous compositions ASHLAND OIL, INC. (US) 1992-05-26 US claimed
EP-0341375-A2 Compatible polyol blends for high modulus polyurethane compositions Ashland Oil, Inc. (US) 1989-11-15 EP claimed
US-4826885-A REACTION INJECTION MOLDING ASHLAND OIL, INC. (US) 1989-05-02 US claimed