Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7862111 | 0.99 | ACACB (0.45) | ACACBMAPTPOLBLMNAKMT2A | |
| SCHEMBL7869835 | 0.93 | MAPT (0.49) | MAPTPOLBLMNAKMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL7862079 | 0.92 | MAPT (0.48) | MAPTPOLBLMNAKMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL7867062 | 0.91 | MAPT (0.46) | ACACBMAPTPOLBLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL7874015 | 0.89 | POLB (0.44) | ACACBMAPTPOLBLMNAKMT2A | |
| SCHEMBL7862201 | 0.85 | ACACB (0.47) | ACACBMAPTPOLBLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL7869860 | 0.84 | ACACB (0.46) | ACACBMAPTPOLBLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL7869908 | 0.84 | NAMPT (0.43) | ACACBMAPTPOLBLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL7862065 | 0.84 | MAPT (0.49) | MAPTPOLBLMNAKMT2AHSD17B10 | |
| SCHEMBL7869785 | 0.78 | HRH3 (0.49) | MAPTPOLBLMNAKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300368-B1 | FOR THERAPY OF ATRIAL ARRHYTHMIA | MITSUI CHEMICALS, INC. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0968999-A1 | Anilide derivatives and antiarrhythmic agents containing the same | Mitsui Chemicals, Inc. (JP) | 2000-01-05 | — | — | EP | disclosed |