Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 19/20 | 0.81 |
| ▸ | LY96 | Q9Y6Y9 | 6/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7858795 | 1.00 | TLR4 (0.81) | TLR4LY96 | |
| SCHEMBL7866952 | 1.00 | TLR4 (0.81) | TLR4LY96 | |
| SCHEMBL7858800 | 1.00 | TLR4 (0.81) | TLR4LY96 | |
| SCHEMBL7858806 | 1.00 | TLR4 (0.81) | TLR4LY96 | |
| SCHEMBL7865447 | 1.00 | TLR4 (0.81) | TLR4LY96 | |
| SCHEMBL7865406 | 1.00 | TLR4 (0.81) | TLR4LY96 | |
| SCHEMBL7864286 | 1.00 | TLR4 (0.81) | TLR4LY96 | |
| SCHEMBL7158457 | 1.00 | TLR4 (0.81) | TLR4LY96 | |
| SCHEMBL7864283 | 1.00 | TLR4 (0.81) | TLR4LY96 | |
| SCHEMBL7865413 | 1.00 | TLR4 (0.81) | TLR4LY96 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303347-B1 | VACCINES | CORIXA CORPORATION | 2001-10-16 | — | — | US | disclosed |