Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 17/20 | 0.59 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3755458 | 0.81 | PIK3CA (0.61) | PIK3CACREBBPMTOR | |
| SCHEMBL3753626 | 0.80 | PIK3CA (0.79) | PIK3CAMTOR | |
| SCHEMBL3747280 | 0.79 | PIK3CA (0.70) | PIK3CACREBBPMTOR | |
| SCHEMBL3750912 | 0.79 | PIK3CA (0.63) | PIK3CACREBBP | |
| SCHEMBL3758971 | 0.79 | PIK3CA (0.72) | PIK3CACREBBP | |
| SCHEMBL3754895 | 0.79 | PIK3CA (0.63) | PIK3CACREBBPMTOR | |
| SCHEMBL3753487 | 0.78 | PIK3CA (0.74) | PIK3CAMTOR | |
| SCHEMBL3752699 | 0.78 | PIK3CA (0.67) | PIK3CACREBBPMTOR | |
| SCHEMBL2726184 | 0.78 | PIK3CA (0.71) | PIK3CACREBBP | |
| SCHEMBL3756297 | 0.78 | PIK3CA (0.62) | PIK3CACREBBPMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118208-A1 | BENZOXAZEPIN-4- (5H) -YL DERIVATIVES AND THEIR USE TO TREAT CANCER | EXELIXIS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |