Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7564177 | 0.92 | FNTA (0.38) | FNTAFNTB | |
| SCHEMBL7565353 | 0.90 | FNTA (0.33) | CAPN1FNTAFNTBMAPK1 | |
| SCHEMBL7867254 | 0.85 | FNTA (0.35) | CAPN1FNTAFNTB | |
| SCHEMBL7565485 | 0.83 | FNTA (0.48) | FNTAFNTB | |
| SCHEMBL7567718 | 0.82 | FNTA (0.32) | CAPN1FNTAFNTB | |
| SCHEMBL7570953 | 0.82 | FNTA (0.41) | FNTAFNTBMAPK1 | |
| SCHEMBL7568380 | 0.81 | GRM2 (0.36) | CAPN1 | |
| SCHEMBL7561389 | 0.81 | CTSA (0.36) | CAPN1MAPK1 | |
| SCHEMBL7692641 | 0.79 | CAPN1 (0.34) | CAPN1FNTAFNTB | |
| SCHEMBL7562210 | 0.78 | FNTA (0.41) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025088-B1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | ASTRAZENECA AB (SE) | 2001-09-05 | — | — | EP | disclosed |