Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7165778 | 0.88 | KMT2A (0.52) | HPGDKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL6815655 | 0.88 | KDM4E (0.53) | HPGDKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL6812148 | 0.85 | KMT2A (0.52) | HPGDKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL6815576 | 0.85 | KDM4E (0.52) | HPGDKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL7939058 | 0.85 | KMT2A (0.52) | HPGDKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL6815964 | 0.85 | NPC1 (0.47) | HPGDKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL6819145 | 0.85 | KMT2A (0.53) | HPGDKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL6814858 | 0.85 | MAPT (0.54) | HPGDKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL6815574 | 0.85 | KMT2A (0.55) | HPGDKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL6815152 | 0.85 | KDM4E (0.55) | HPGDKDM4EALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137645-A2 | ALPHA-METHYLBENZYL-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000034260-A2 | ALPHA-METHYLBENZYL-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |