Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | MPL | P40238 | 2/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 3/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.32 |
| ▸ | OXTR | P30559 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1264478 | 0.75 | HDAC6 (0.54) | HDAC6HDAC8HDAC1HDAC3HDAC2 | |
| SCHEMBL12210474 | 0.70 | HDAC6 (0.47) | HDAC6HDAC8HDAC1HDAC3HDAC2 | |
| SCHEMBL7866689 | 0.68 | HDAC6 (0.49) | HDAC6MAPT | |
| SCHEMBL1263507 | 0.68 | HDAC6 (0.52) | HDAC6HDAC8HDAC1HDAC3HDAC2 | |
| SCHEMBL7868064 | 0.67 | HDAC6 (0.45) | HDAC6HDAC8HDAC1HDAC3HDAC2 | |
| SCHEMBL1263371 | 0.63 | HDAC6 (0.52) | HDAC6HDAC8HDAC1HDAC3MAPT | |
| SCHEMBL12868966 | 0.61 | HDAC6 (0.56) | HDAC6HDAC8HDAC1HDAC3KDM1A | |
| SCHEMBL1174023 | 0.61 | HDAC6 (0.53) | HDAC6HDAC8HDAC1HDAC3MAPT | |
| SCHEMBL16330350 | 0.60 | PPARG (0.41) | HDAC6 | |
| SCHEMBL1263752 | 0.59 | MEN1 (0.52) | HDAC6HDAC8HDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151318-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-12-29 | — | — | WO | disclosed |