Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | ARG2 | P78540 | 4/20 | 0.46 |
| ▸ | ARG1 | P05089 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.42 |
| ▸ | KDM5A | P29375 | 2/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10073275 | 1.00 | GSR (0.50) | GSRMETAP1ARG2ARG1SIGMAR1 | |
| SCHEMBL23740241 | 1.00 | GSR (0.50) | GSRMETAP1ARG2ARG1SIGMAR1 | |
| SCHEMBL5843553 | 0.95 | METAP1 (0.47) | GSRMETAP1ARG2ARG1SIGMAR1 | |
| SCHEMBL5843561 | 0.95 | METAP1 (0.47) | GSRMETAP1ARG2ARG1SIGMAR1 | |
| SCHEMBL18762478 | 0.93 | GSR (0.48) | GSRMETAP1ARG2ARG1SLC1A3 | |
| SCHEMBL28868842 | 0.91 | GSR (0.55) | GSRARG2ARG1SLC1A3SLC1A2 | |
| SCHEMBL2877061 | 0.87 | METAP1 (0.55) | GSRMETAP1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1224024 | 0.87 | METAP1 (0.55) | GSRMETAP1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1768565 | 0.87 | METAP1 (0.55) | GSRMETAP1SLC1A3SLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL2033821 | 0.85 | METAP1 (0.53) | GSRMETAP1SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012051663-A1 | ANTIMICROBIAL COMPOUNDS | MONASH UNIVERSITY (AU) | 2012-04-26 | — | — | WO | disclosed |
| WO-2010130007-A1 | ANTIMICROBIAL COMPOUNDS | MONASH UNIVERSITY (AU) | 2010-11-18 | — | — | WO | disclosed |