SCHEMBL786870

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1670322	0.86	HDAC1 (0.62)	HDAC1HDAC6HDAC8HDAC3HDAC2
	SCHEMBL31476426	0.86	HDAC1 (0.62)	HDAC1HDAC6HDAC8HDAC3HDAC2
	SCHEMBL3797439	0.83	HDAC1 (0.60)	HDAC1HDAC6HDAC8CYP1A2CYP3A4
	SCHEMBL31058502	0.81	HDAC1 (0.57)	HDAC1HDAC6HDAC8CYP1A2CYP3A4
	SCHEMBL3793050	0.77	HTR2A (0.56)	HDAC1HDAC6HDAC8CYP1A2CYP3A4
	SCHEMBL23950253	0.77	HDAC1 (1.00)	HDAC1HDAC6HDAC8HDAC3HDAC2
	SCHEMBL30051193	0.77	HDAC1 (1.00)	HDAC1HDAC6HDAC8HDAC3HDAC2
	SCHEMBL16035596	0.77	CYP1A2 (0.49)	HDAC1HDAC6CYP1A2CYP3A4CYP2D6
	SCHEMBL16030871	0.77	CYP1A2 (0.55)	HDAC1HDAC6HDAC8CYP1A2CYP3A4
	SCHEMBL29483472	0.77	HDAC1 (0.65)	HDAC1HDAC6HDAC8HDAC3HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.