⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6605974 | 0.82 | TSHR (0.30) | — | |
| SCHEMBL10078640 | 0.71 | — | — | |
| SCHEMBL3936228 | 0.69 | — | — | |
| SCHEMBL6545092 | 0.67 | HIF1A (0.56) | — | |
| SCHEMBL1626828 | 0.67 | — | — | |
| SCHEMBL7405710 | 0.67 | — | — | |
| SCHEMBL11390774 | 0.65 | TSHR (0.52) | — | |
| SCHEMBL431901 | 0.65 | HIF1A (0.53) | — | |
| SCHEMBL127719 | 0.65 | HIF1A (0.53) | — | |
| SCHEMBL9297651 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1117442-A1 | DRY POWDER ACTIVE AGENT PULMONARY DELIVERY | Inhale Therapeutic Systems, Inc. (US) | 2001-07-25 | — | — | EP | claimed |
| WO-2000015262-A1 | DRY POWDER ACTIVE AGENT PULMONARY DELIVERY | INHALE THERAPEUTIC SYSTEMS, INC. (US) | 2000-03-23 | — | — | WO | claimed |
| CN-116635009-A | Compositions and methods for delivering anticancer agents with improved therapeutic index | 纳米科技制药公司 | 2023-08-22 | — | — | CN | disclosed |
| US-11730732-B2 | Oral suspension of temozolomide | ORPHELIA PHARMA (FR) | 2023-08-22 | — | — | US | disclosed |
| EP-1117442-A1 | DRY POWDER ACTIVE AGENT PULMONARY DELIVERY | Inhale Therapeutic Systems, Inc. (US) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000015262-A1 | DRY POWDER ACTIVE AGENT PULMONARY DELIVERY | INHALE THERAPEUTIC SYSTEMS, INC. (US) | 2000-03-23 | — | — | WO | disclosed |