⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7395053 | 1.00 | — | — | |
| SCHEMBL28304902 | 1.00 | — | — | |
| SCHEMBL3237456 | 1.00 | — | — | |
| SCHEMBL2635436 | 0.97 | — | — | |
| SCHEMBL3046113 | 0.97 | — | — | |
| SCHEMBL300712 | 0.97 | — | — | |
| SCHEMBL23363809 | 0.93 | — | — | |
| SCHEMBL3684002 | 0.93 | SUCNR1 (0.35) | — | |
| SCHEMBL8071886 | 0.93 | SUCNR1 (0.35) | — | |
| SCHEMBL28775385 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117715658-A | Method for inhibiting RAS | 锐新医药公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-111356680-B | Selective inhibitors of NLRP3 inflammasome | 诺瑟拉有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-111356680-A | Selective inhibitors of NLRP3inflammasome | 诺瑟拉有限公司 | 2020-06-30 | — | — | CN | disclosed |
| CN-106146511-A | Pyrazolopyrimidine derivative, preparation method, pharmaceutical composition and purposes | 安润医药科技（苏州）有限公司 | 2016-11-23 | — | — | CN | disclosed |
| US-6300514-B1 | INHIBITING MATRIX METALLOPROTEINASES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0994104-A1 | ARYL (SULFIDE, SULFOXIDE AND SULFONE) DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | disclosed |