SCHEMBL7869065

SCHEMBL7869065

COC(=O)[C@H](CCSC)NC(=O)c1ccc(CCC(=O)NCCCCC2CCCCC2)cc1-c1ccccc1C

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 3/20 0.57
FNTB P49356 3/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6625718 0.93 FNTA (0.66) FNTAFNTB
Lithium Ion SCHEMBL7869129 0.92 FNTA (0.57) FNTAFNTB
SCHEMBL628594 0.91 FNTA (0.59) FNTAFNTB
SCHEMBL628891 0.86 FNTA (0.67) FNTAFNTB
SCHEMBL7870317 0.85 FNTA (0.61) FNTAFNTB
SCHEMBL7907257 0.84 FNTA (0.59) FNTAFNTB
SCHEMBL629019 0.83 FNTA (0.69) FNTAFNTB
SCHEMBL7918034 0.83 FNTA (0.72) FNTAFNTB
SCHEMBL7918026 0.83 FNTA (0.72) FNTAFNTB
SCHEMBL7871113 0.82 FNTA (0.55) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6310095-B1 INHIBITING OR TREATING CANCER, TREATING INTIMAL HYPERPLASIA ASSOCIATED WITH RESTENOSIS AND ATHEROSCLEROSIS, INHIBITING POST-TRANSLATIONAL MODIFICATION OF ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE AND/OR GERANYLGERANYLTRANSFERASE UNIVERSITY OF PITTSBURGH 2001-10-30 US disclosed