Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6625436 | 0.91 | FNTA (0.64) | FNTAFNTB | |
| Lithium Ion SCHEMBL7870195 | 0.91 | FNTA (0.70) | FNTAFNTB | |
| SCHEMBL6625678 | 0.82 | FNTA (0.78) | FNTAFNTB | |
| SCHEMBL17145315 | 0.81 | FNTA (0.60) | FNTAFNTB | |
| SCHEMBL16160195 | 0.81 | FNTA (0.60) | FNTAFNTB | |
| SCHEMBL6782105 | 0.81 | FNTA (0.71) | FNTAFNTB | |
| Lithium Ion SCHEMBL7862360 | 0.80 | FNTA (0.76) | FNTAFNTB | |
| Lithium Ion SCHEMBL7869159 | 0.79 | FNTA (0.58) | FNTAFNTB | |
| Lithium Ion SCHEMBL7871124 | 0.79 | FNTA (0.62) | FNTAFNTB | |
| Lithium Ion SCHEMBL6628591 | 0.79 | FNTA (0.85) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310095-B1 | INHIBITING OR TREATING CANCER, TREATING INTIMAL HYPERPLASIA ASSOCIATED WITH RESTENOSIS AND ATHEROSCLEROSIS, INHIBITING POST-TRANSLATIONAL MODIFICATION OF ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE AND/OR GERANYLGERANYLTRANSFERASE | UNIVERSITY OF PITTSBURGH | 2001-10-30 | — | — | US | disclosed |