Sugi Predict

Sugi Predict / Compounds / Lithium

Lithium

Lithium

SCHEMBL7869166

CSCC[C@H](NC(=O)c1ccc(CN(Cc2ccccc2)c2ccsc2C)cc1-c1ccccc1C)C(=O)O.[Li]

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 3/20 0.61
▸ FNTB P49356 3/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6626503 0.99 FNTA (0.62) FNTAFNTB
Lithium SCHEMBL7870245 0.89 FNTA (0.62) FNTAFNTB
SCHEMBL6626705 0.89 FNTA (0.63) FNTAFNTB
SCHEMBL6626709 0.89 FNTA (0.63) FNTAFNTB
SCHEMBL7870243 0.88 FNTA (0.62) FNTAFNTB
SCHEMBL6625372 0.87 FNTA (0.61) FNTAFNTB
SCHEMBL6625368 0.87 FNTA (0.61) FNTAFNTB
SCHEMBL6626499 0.87 FNTA (0.63) FNTAFNTB
Lithium SCHEMBL7871132 0.86 FNTA (0.60) FNTAFNTB
SCHEMBL6625678 0.86 FNTA (0.78) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6310095-B1 INHIBITING OR TREATING CANCER, TREATING INTIMAL HYPERPLASIA ASSOCIATED WITH RESTENOSIS AND ATHEROSCLEROSIS, INHIBITING POST-TRANSLATIONAL MODIFICATION OF ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE AND/OR GERANYLGERANYLTRANSFERASE UNIVERSITY OF PITTSBURGH 2001-10-30 — — US disclosed