Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 1/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 14/20 | 0.51 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.37 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3752585 | 0.94 | PRKDC (0.57) | PRKDCPIK3CARIPK1GPR142PIK3CG | |
| SCHEMBL3750502 | 0.94 | PRKDC (0.55) | PRKDCPIK3CARIPK1GPR142PIK3CG | |
| SCHEMBL3754528 | 0.94 | PRKDC (0.57) | PRKDCPIK3CARIPK1GPR142PIK3CG | |
| SCHEMBL3756049 | 0.91 | PRKDC (0.56) | PRKDCPIK3CARIPK1PIK3CG | |
| SCHEMBL3755747 | 0.91 | PRKDC (0.56) | PRKDCPIK3CARIPK1PIK3CG | |
| SCHEMBL3755143 | 0.91 | PRKDC (0.54) | PRKDCPIK3CARIPK1GPR142PIK3CG | |
| SCHEMBL3747626 | 0.91 | PRKDC (0.54) | PRKDCPIK3CARIPK1GPR142PIK3CG | |
| SCHEMBL3754870 | 0.91 | PRKDC (0.56) | PRKDCPIK3CARIPK1GPR142PIK3CG | |
| SCHEMBL3751119 | 0.90 | PRKDC (0.53) | PRKDCPIK3CARIPK1GPR142PIK3CG | |
| SCHEMBL3760514 | 0.89 | PRKDC (0.54) | PRKDCPIK3CARIPK1GPR142PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118208-A1 | BENZOXAZEPIN-4- (5H) -YL DERIVATIVES AND THEIR USE TO TREAT CANCER | EXELIXIS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |