⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiazolidine SCHEMBL5484388 | 0.96 | — | — | |
| Thiazolidine SCHEMBL131493 | 0.96 | — | — | |
| Thiazolidine SCHEMBL7360 | 0.96 | — | — | |
| Thiazolidine SCHEMBL2914331 | 0.93 | — | — | |
| Thiazolidine SCHEMBL2914332 | 0.93 | — | — | |
| Thiazolidine SCHEMBL25231396 | 0.93 | — | — | |
| Thiazolidine SCHEMBL9270747 | 0.93 | — | — | |
| Thiazolidine SCHEMBL6687453 | 0.93 | — | — | |
| Thiazolidine SCHEMBL2158442 | 0.93 | — | — | |
| Thiazolidine SCHEMBL9034521 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310180-B1 | PEPTIDE BIOSYNTHESIS REQUIRING NEITHER PROTECTION NOR ACTIVE C-ALPHA CARBOXYL GROUPS BY COUPLING PEPTIDES BY REACTING A 1-AMINO-2-MERCAPTO ALKYL ATTACHED TO ONE PEPTIDE WITH THE CARBOXY GROUP OF THE OTHER; REARRANGEMENT; STABILITY | VANDERBILT UNIVERSITY | 2001-10-30 | — | — | US | disclosed |
| US-5589356-A | CYCLIZATION | VANDERBILT UNIVERSITY (US) | 1996-12-31 | — | — | US | disclosed |
| WO-1995000846-A1 | DOMAIN LIGATION STRATEGY TO ENGINEER PROTEINS WITH UNUSUAL ARCHITECTURES | TAM JAMES P (US) | 1995-01-05 | — | — | WO | disclosed |