Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 11/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 9/20 | 0.44 |
| ▸ | NPY1R | P25929 | 8/20 | 0.44 |
| ▸ | NMT2 | O60551 | 1/20 | 0.43 |
| ▸ | NMT1 | P30419 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 6/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | FURIN | P09958 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7869393 | 1.00 | NPY4R (0.44) | NPY4RNPY5RNPY1RNMT2NMT1 | |
| SCHEMBL30129496 | 0.92 | NPY4R (0.43) | NPY4RNPY5RNPY1RNPY2RNPBWR1 | |
| SCHEMBL30129763 | 0.90 | NPY4R (0.42) | NPY4RNPY5RNPY1RNPY2RNPBWR1 | |
| SCHEMBL7861255 | 0.89 | NPY4R (0.47) | NPY4RNPY5RNPY1RNMT2NMT1 | |
| SCHEMBL7861254 | 0.89 | NPY4R (0.47) | NPY4RNPY5RNPY1RNMT2NMT1 | |
| SCHEMBL30519038 | 0.89 | NMT1 (0.42) | NPY4RNPY5RNPY1RNMT2NMT1 | |
| SCHEMBL31589116 | 0.88 | NMT1 (0.41) | NPY4RNPY5RNPY1RNMT2NMT1 | |
| SCHEMBL31691754 | 0.88 | NPY4R (0.42) | NPY4RNPY5RNPY1RNMT2NMT1 | |
| SCHEMBL30372208 | 0.88 | NPY4R (0.42) | NPY4RNPY5RNPY1RNMT2NMT1 | |
| SCHEMBL29608297 | 0.87 | NPY4R (0.49) | NPY4RNPY5RNPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303116-B1 | CAPABLE OF TRANSDUCING THERAPEUTIC GENES INTO NON-DIVIDING CELLS. | THOMAS JEFFERSON UNIVERSITY | 2001-10-16 | — | — | US | disclosed |