Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 19/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 19/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 19/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 19/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31574699 | 0.88 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL6360155 | 0.88 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL7786813 | 0.84 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7792692 | 0.84 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7420776 | 0.84 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6546375 | 0.81 | PDE4B (0.58) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6823874 | 0.80 | PDE4B (0.53) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6821428 | 0.80 | PDE4B (0.53) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7117812 | 0.80 | PDE4B (0.53) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7425652 | 0.80 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636025-B1 | COMPOUNDS USEFUL FOR TREATING ALLERGIC OR INFLAMMATORY DISEASES | SMITHKLINE BEECHAM CORP (US) | 2001-07-18 | — | — | EP | claimed |