Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.68 |
| ▸ | SLC29A1 | Q99808 | 6/20 | 0.50 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.43 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.43 |
| ▸ | SLC28A2 | O43868 | 3/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7869884 | 1.00 | HDAC6 (0.68) | HDAC6SLC29A1HSPA5HSPA8SLC28A2 | |
| SCHEMBL7809936 | 0.97 | HDAC6 (0.70) | HDAC6SLC29A1HSPA5HSPA8SLC28A2 | |
| SCHEMBL7809935 | 0.97 | HDAC6 (0.70) | HDAC6SLC29A1HSPA5HSPA8SLC28A2 | |
| SCHEMBL7807814 | 0.93 | HDAC6 (0.72) | HDAC6SLC29A1HSPA5HSPA8SLC28A2 | |
| SCHEMBL7807811 | 0.93 | HDAC6 (0.72) | HDAC6SLC29A1HSPA5HSPA8SLC28A2 | |
| SCHEMBL7801027 | 0.89 | HDAC6 (0.75) | HDAC6SLC29A1HSPA5HSPA8SLC28A2 | |
| SCHEMBL7801031 | 0.89 | HDAC6 (0.75) | HDAC6SLC29A1HSPA5HSPA8SLC28A2 | |
| SCHEMBL7812660 | 0.89 | HDAC6 (0.72) | HDAC6SLC29A1HSPA5HSPA8SLC28A2 | |
| SCHEMBL7812665 | 0.89 | HDAC6 (0.72) | HDAC6SLC29A1HSPA5HSPA8SLC28A2 | |
| SCHEMBL7116192 | 0.87 | HDAC6 (0.51) | HDAC6SLC29A1HSPA8FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6307043-B1 | FOR TREATMENT OR PROPHYLAXIS OF HERPES VIRAL INFECTIONS | GLAXO WELLCOME INC. | 2001-10-23 | — | — | US | disclosed |
| US-6077832-A | FOR THERAPY AND PROPHYLAXIS OF HERPES VIRUS INFECTION | GLAXO WELLCOME INC. (US) | 2000-06-20 | — | — | US | disclosed |
| EP-0769017-B1 | THERAPEUTIC COMPOUNDS | WELLCOME FOUND (GB) | 2000-05-24 | — | — | EP | disclosed |
| US-5998605-A | Antiviral benzimidazole nucleoside analogues and method for their preparation | GLAXO WELLCOME INC. (US) | 1999-12-07 | — | — | US | disclosed |