Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8015894 | 0.95 | SMN1; SMN2 (0.70) | SMN1; SMN2TSHRKDM4ELMNAALDH1A1 | |
| SCHEMBL7868735 | 0.93 | SMN1; SMN2 (0.68) | SMN1; SMN2TSHRKDM4ELMNAALDH1A1 | |
| SCHEMBL7870760 | 0.91 | SMN1; SMN2 (0.71) | SMN1; SMN2TSHRLMNAALDH1A1MAPT | |
| SCHEMBL8016819 | 0.88 | SMN1; SMN2 (0.72) | SMN1; SMN2TSHRKDM4ELMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL7870728 | 0.88 | SMN1; SMN2 (0.71) | SMN1; SMN2TSHRKDM4ELMNAALDH1A1 | |
| SCHEMBL7869947 | 0.86 | SMN1; SMN2 (0.65) | SMN1; SMN2TSHRLMNAALDH1A1MAPT | |
| SCHEMBL7866953 | 0.83 | SMN1; SMN2 (0.67) | SMN1; SMN2TSHRLMNAALDH1A1MAPT | |
| SCHEMBL7862101 | 0.83 | SMN1; SMN2 (0.67) | SMN1; SMN2TSHRKDM4ELMNAALDH1A1 | |
| SCHEMBL7869899 | 0.83 | SMN1; SMN2 (0.74) | SMN1; SMN2TSHRLMNAALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7862199 | 0.82 | SMN1; SMN2 (0.66) | SMN1; SMN2TSHRLMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300368-B1 | FOR THERAPY OF ATRIAL ARRHYTHMIA | MITSUI CHEMICALS, INC. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0968999-A1 | Anilide derivatives and antiarrhythmic agents containing the same | Mitsui Chemicals, Inc. (JP) | 2000-01-05 | — | — | EP | disclosed |