SCHEMBL786993

SCHEMBL786993

NC1=NC2(CCN2)C2=NC=NC2=N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2885121 0.72
SCHEMBL9563448 0.70
SCHEMBL1524914 0.66
SCHEMBL8970996 0.66
SCHEMBL4062710 0.58
SCHEMBL3922434 0.56
SCHEMBL4280534 0.56
SCHEMBL7718436 0.54
SCHEMBL17744967 0.52
SCHEMBL18047916 0.52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240240161-A1 DP04 POLYMERASE VARIANTS Roche Sequencing Solutions, Inc. 2024-07-18 US disclosed
EP-3619321-B1 DP04 POLYMERASE VARIANTS ROCHE DIAGNOSTICS GMBH (DE) 2024-07-17 EP disclosed
US-12037577-B2 DPO4 polymerase variants Roche Sequencing Solutions, Inc. (US) 2024-07-16 US disclosed
EP-4396376-A1 AMPLITUDE MODULATION FOR ACCELERATED BASE CALLING ILLUMINA, INC. (US) 2024-07-10 EP disclosed
EP-4347885-A1 SYSTEMS AND METHODS FOR SEQUENCING NUCLEOTIDES USING TWO OPTICAL CHANNELS ILLUMINA, INC. (US) 2024-04-10 EP disclosed
WO-2024073278-A1 DETECTING AND GENOTYPING VARIABLE NUMBER TANDEM REPEATS ILLUMINA, INC. (US) 2024-04-04 WO disclosed
WO-2024072685-A1 FAST PULSING FOR NANOPORE SENSORS ILLUMINA, INC. (US) 2024-04-04 WO disclosed
US-20240110889-A1 FAST PULSING FOR NANOPORE SENSORS ILLUMINA, INC. 2024-04-04 US disclosed
EP-4341435-A1 METHODS OF BASE CALLING NUCLEOBASES Illumina, Inc. (US) 2024-03-27 EP disclosed
WO-2024010809-A2 METHODS AND SYSTEMS FOR DETECTING RECOMBINATION EVENTS ILLUMINA SOFTWARE, INC. (US) 2024-01-11 WO disclosed
US-20120088235-A1 HIGH THROUGHPUT NUCLEIC ACID SEQUENCING BY EXPANSION AND RELATED METHODS STRATOS GENOMICS, INC. (US) 2012-04-12 US disclosed
US-20120071330-A1 MULTIPLEXED IDENTIFICATION OF NUCLEIC ACID SEQUENCES STRATOS GENOMICS INC. (US) 2012-03-22 US disclosed
WO-2012003330-A2 MULTIPLEXED IDENTIFICATION OF NUCLEIC ACID SEQUENCES STRATOS GENOMICS, INC (US) 2012-01-05 WO disclosed
US-20110251079-A1 HIGH THROUGHPUT NUCLEIC ACID SEQUENCING BY EXPANSION STRATOS GENOMICS, INC. (US) 2011-10-13 US disclosed
US-20110237787-A1 HIGH THROUGHPUT NUCLEIC ACID SEQUENCING BY EXPANSION STRATOS GENOMICS, INC. (US) 2011-09-29 US disclosed
US-7939259-B2 High throughput nucleic acid sequencing by expansion STRATOS GENOMICS, INC. (US) 2011-05-10 US disclosed
US-20100297644-A1 HIGH THROUGHPUT NUCLEIC ACID SEQUENCING BY SPACING STRATOS GENOMICS INC. (US) 2010-11-25 US disclosed
EP-2171088-A2 HIGH THROUGHPUT NUCLEIC ACID SEQUENCING BY EXPANSION Stratos Genomics Inc. (US) 2010-04-07 EP disclosed
US-20090035777-A1 HIGH THROUGHPUT NUCLEIC ACID SEQUENCING BY EXPANSION Roche Sequencing Solutions, Inc. 2009-02-05 US disclosed
WO-2008157696-A2 HIGH THROUGHPUT NUCLEIC ACID SEQUENCING BY EXPANSION STRATOS GENOMICS INC. (US) 2008-12-24 WO disclosed