SCHEMBL7869972

SCHEMBL7869972

O=C1OC(=O)C2C3C=CC(C3O)C12

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
GMNN O75496 1/20 0.36
PPM1B O75688 1/20 0.36
LMNA P02545 1/20 0.36
PPP1CC P36873 1/20 0.36
TFPI2 P48307 1/20 0.36
RAB9A P51151 1/20 0.36
PPP5C P53041 1/20 0.36
PPP1CA P62136 1/20 0.36
PMP22 Q01453 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TP53 P04637 1/20 0.36
CYP2D6 P10635 1/20 0.36
NFKB1 P19838 1/20 0.36
THPO P40225 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19057999 0.84 SMN1; SMN2 (0.42) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL671860 0.84 SMN1; SMN2 (0.42) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL23139797 0.84 SMN1; SMN2 (0.42) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL15451887 0.84 SMN1; SMN2 (0.42) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL14297393 0.81 KDM4E (0.40) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL9458294 0.81 KDM4E (0.40) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL2334133 0.77 SMN1; SMN2 (0.37) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL14216716 0.75 KDM4E (0.36) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL14197579 0.75 KDM4E (0.36) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL1150234 0.75 TDP1 (0.45) KDM4EGMNNPPM1BLMNAPPP1CC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6303744-B1 NOVEL DICARBOXYLIC ENDCAP SUCH AS 7-HYDROXY-5-NORBORNENE-2,3-DICARBOXYLIC ANHYDRIDE AND 7,7-DIFLOURO-5-NORBORNENE-2,3-DICARBOXYLIC ANHYDRIDE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION 2001-10-16 US claimed
US-20170047142-A1 USE OF A VITRIMER-TYPE THERMOSETTING RESIN COMPOSITION FOR MANUFACTURING ELECTRICAL INSULATION PARTS ARKEMA FRANCE (FR) 2017-02-16 US disclosed
US-20170047142-A1 USE OF A VITRIMER-TYPE THERMOSETTING RESIN COMPOSITION FOR MANUFACTURING ELECTRICAL INSULATION PARTS ARKEMA FRANCE (FR) 2017-02-16 US disclosed
US-6303744-B1 NOVEL DICARBOXYLIC ENDCAP SUCH AS 7-HYDROXY-5-NORBORNENE-2,3-DICARBOXYLIC ANHYDRIDE AND 7,7-DIFLOURO-5-NORBORNENE-2,3-DICARBOXYLIC ANHYDRIDE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION 2001-10-16 US disclosed
US-6274699-B1 ENDCAPPING WITH A ISOBENZOFURAN COMPOUND THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION 2001-08-14 US disclosed