Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 5/20 | 0.67 |
| ▸ | TACR1 | P25103 | 3/20 | 0.67 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.47 |
| ▸ | TACR3 | P29371 | 5/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864418 | 0.92 | TACR2 (0.65) | TACR2TACR1TACR3CCR5 | |
| SCHEMBL7870009 | 0.89 | TACR2 (0.73) | TACR2TACR1TACR3 | |
| SCHEMBL14089179 | 0.88 | TACR2 (0.75) | TACR2TACR1TACR3 | |
| SCHEMBL7864552 | 0.88 | TACR2 (0.65) | TACR2TACR1 | |
| SCHEMBL6952599 | 0.86 | TACR2 (0.73) | TACR2TACR1TACR3 | |
| SCHEMBL6588311 | 0.82 | TACR2 (0.69) | TACR2TACR1TACR3 | |
| SCHEMBL7871894 | 0.81 | TACR2 (0.65) | TACR2TACR1TACR3 | |
| SCHEMBL7871897 | 0.81 | TACR2 (0.65) | TACR2TACR1TACR3 | |
| SCHEMBL7873231 | 0.81 | TACR2 (0.65) | TACR2TACR1TACR3 | |
| SCHEMBL7873296 | 0.81 | TACR2 (0.63) | TACR2TACR1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808303-B1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ASTRAZENECA AB (SE) | 2001-06-20 | — | — | EP | disclosed |
| EP-0808303-A1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ZENECA LIMITED (GB) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024582-A1 | 5-(4-SUBST.-PIPERIDINYL-1)-3-ARYL-PENTANOIC ACID DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONIST | ZENECA LIMITED (GB) | 1996-08-15 | — | — | WO | disclosed |