Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.33 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27499132 | 0.83 | GABRR1 (0.31) | OR51E2GLRA1SLC6A9ACE | |
| SCHEMBL18668788 | 0.80 | SMN1; SMN2 (0.37) | OR51E2GLRA1SLC6A9ACESLC1A1 | |
| SCHEMBL4929942 | 0.80 | GABRR1 (0.38) | OR51E2GLRA1SLC6A9ACE | |
| SCHEMBL28446696 | 0.77 | MEN1 (0.35) | OR51E2ACE | |
| SCHEMBL30782967 | 0.77 | CHRM1 (0.41) | SLC1A1 | |
| SCHEMBL17701380 | 0.75 | OR51E2 (0.39) | OR51E2SLC1A1SRRUSP2SLCO1B1 | |
| SCHEMBL4387726 | 0.74 | SLC1A1 (0.50) | SLC1A1 | |
| SCHEMBL28153073 | 0.73 | GLRA1 (0.38) | OR51E2GLRA1SLC6A9 | |
| SCHEMBL8998222 | 0.73 | MAPT (0.47) | OR51E2GLRA1SLC6A9 | |
| SCHEMBL9450194 | 0.71 | TSHR (0.42) | OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310180-B1 | PEPTIDE BIOSYNTHESIS REQUIRING NEITHER PROTECTION NOR ACTIVE C-ALPHA CARBOXYL GROUPS BY COUPLING PEPTIDES BY REACTING A 1-AMINO-2-MERCAPTO ALKYL ATTACHED TO ONE PEPTIDE WITH THE CARBOXY GROUP OF THE OTHER; REARRANGEMENT; STABILITY | VANDERBILT UNIVERSITY | 2001-10-30 | — | — | US | disclosed |