⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2386768 | 0.78 | — | — | |
| SCHEMBL10620464 | 0.75 | — | — | |
| SCHEMBL16671217 | 0.75 | — | — | |
| SCHEMBL786907 | 0.75 | — | — | |
| SCHEMBL3763923 | 0.75 | — | — | |
| SCHEMBL3077020 | 0.75 | — | — | |
| SCHEMBL2917853 | 0.73 | — | — | |
| SCHEMBL2161386 | 0.72 | — | — | |
| SCHEMBL28983346 | 0.72 | — | — | |
| SCHEMBL29068180 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114432901-A | Composite membrane with acid resistance and alkali resistance as well as preparation method and application thereof | 中国石油化工股份有限公司 | 2022-05-06 | — | — | CN | disclosed |
| EP-2439202-B1 | INHIBITOR COMPOUNDS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | SALVAT LAB SA (ES) | 2016-04-20 | — | — | EP | disclosed |
| CN-102834385-B | Inhibitor compounds of 11-beta-hydroxysteroid dehydrogenase type 1 | LABORATORIOS SALVAT, S.A. (ES) | 2016-03-09 | — | — | CN | disclosed |
| US-8859812-B2 | Compound reagents and method for synthesizing enantiomerically enriched amino acids | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-10-14 | — | — | US | disclosed |
| US-8822452-B2 | Inhibitor compounds of 11-beta-hydroxysteroid dehydrogenase type 1 | LABORATORIOS SALVAT, S.A. (ES) | 2014-09-02 | — | — | US | disclosed |
| US-20130303522-A1 | INHIBITOR COMPOUNDS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | LABORATORIOS SALVAT, S.A. (ES) | 2013-11-14 | — | — | US | disclosed |
| US-8524894-B2 | Inhibitor compounds of 11-beta-hydroxysteroid dehydrogenase type 1 | LABORATORIOS SALVAT, S.A. (ES) | 2013-09-03 | — | — | US | disclosed |
| US-20130066109-A1 | COMPOUNDS AND RELATED METHODS OF USE | PRESIDENTS AND FELLOWS OF HARVARD COLLEGE (US) | 2013-03-14 | — | — | US | disclosed |
| CN-102834385-A | Inhibitor compounds of 11-beta-hydroxysteroid dehydrogenase type 1 | SALVAT LAB SA | 2012-12-19 | — | — | CN | disclosed |
| US-20120071466-A1 | INHIBITOR COMPOUNDS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | LABORATORIOS SALVAT, S.A. (ES) | 2012-03-22 | — | — | US | disclosed |
| WO-2010055376-A1 | CHIRAL AMINE-(SULPHUR) UREA DOUBLE FUNCTIONAL CATALYST AND SYNTHESIS METHOD AND USE THEREOF | 帝斯曼知识产权资产管理有限公司 (NL) | 2010-05-20 | — | — | WO | disclosed |
| CN-1118464-C | Noval pyrimidine derivatives and process and preparing thereof | YUHAN CORP (KR) | 2003-08-20 | — | — | CN | disclosed |
| CN-1251586-A | Noval pyrimidine derivatives and process and preparing thereof | YUHAN CORP (KR) | 2000-04-26 | — | — | CN | disclosed |
| US-5639911-A | Hydrazones | CIBA-GEIGY CORPORATION (US) | 1997-06-17 | — | — | US | disclosed |
| US-5461076-A | Inhibitors of S-adenosylmethionine decarboxylase; antitumor agents | NOVARTIS CORPORATION | 1995-10-24 | — | — | US | disclosed |
| US-5395855-A | Antitumor agents | CIBA-GEIGY CORPORATION (US) | 1995-03-07 | — | — | US | disclosed |
| US-5376685-A | Arylhydrazones using as SAMDC inhibitors | CIBA-GEIGY CORPORATION (US) | 1994-12-27 | — | — | US | disclosed |
| US-5238941-A | S-adenosylmethionine decarboxylase inhibitors | CIBA-GEIGY CORPORATION (US) | 1993-08-24 | — | — | US | disclosed |
| US-5118709-A | Decarboxylase enzyme inhibitors; antitumor agents | CIBA-GEIGY CORPORATION (US) | 1992-06-02 | — | — | US | disclosed |
| US-4971986-A | ANTITUMOR AGENTS | CIBA-GEIGY CORPORATION (US) | 1990-11-20 | — | — | US | disclosed |