SCHEMBL7871114

SCHEMBL7871114

CCCC(CC1CCCCC1)NC(C)c1ccc(C(=O)NC(CCSC)C(=O)OC)c(-c2ccccc2C)c1

nearest known ligand 0.58

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 1/20 0.52
FNTB P49356 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6629271 0.93 FNTA (0.60) FNTAFNTB
SCHEMBL630142 0.92 FNTA (0.59) FNTAFNTB
SCHEMBL7870315 0.87 FNTA (0.54) FNTAFNTB
SCHEMBL7867466 0.87 FNTA (0.50) FNTAFNTB
SCHEMBL7862378 0.85 FNTA (0.57) FNTAFNTB
SCHEMBL7874253 0.85 FNTA (0.49) FNTAFNTB
SCHEMBL7903618 0.84 FNTA (0.50) FNTAFNTB
SCHEMBL7869063 0.84 FNTA (0.49) FNTAFNTB
SCHEMBL629649 0.84 FNTA (0.37) FNTAFNTB
SCHEMBL7906871 0.83 FNTA (0.53) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6310095-B1 INHIBITING OR TREATING CANCER, TREATING INTIMAL HYPERPLASIA ASSOCIATED WITH RESTENOSIS AND ATHEROSCLEROSIS, INHIBITING POST-TRANSLATIONAL MODIFICATION OF ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE AND/OR GERANYLGERANYLTRANSFERASE UNIVERSITY OF PITTSBURGH 2001-10-30 US disclosed