Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.44 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.44 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.44 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 10/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 6/20 | 0.44 |
| ▸ | GJB2 | P29033 | 2/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
| ▸ | CDC25B | P30305 | 5/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.38 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7871322 | 1.00 | NT5E (0.45) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7766877 | 0.88 | SSTR1 (0.48) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL7766872 | 0.88 | SSTR1 (0.48) | SSTR1SSTR2SSTR4SSTR3SSTR5 | |
| SCHEMBL22677782 | 0.87 | NT5E (0.49) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL10607794 | 0.84 | SSTR1 (0.58) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL8992046 | 0.84 | SSTR1 (0.58) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL8992050 | 0.84 | SSTR1 (0.58) | NT5ESSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL976471 | 0.83 | NT5E (0.51) | NT5EPTPN1PTPN2PTPN11TACR2 | |
| SCHEMBL976473 | 0.83 | NT5E (0.51) | NT5EPTPN1PTPN2PTPN11TACR2 | |
| SCHEMBL9149779 | 0.82 | NT5E (0.47) | NT5ESSTR1SSTR2SSTR4SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310043-B1 | USING COMPOUNDS WHICH BIND TO TOXINS ASSOCIATED WITH ENTERIC BACTERIAL INFECTION INCLUDING PENTAMERIC TOXINS, FOR EXAMPLE SLTS, SUCH AS THOSE FROM SALMONELLA, CAMYLOBACTER, E-COLI | GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2001-10-30 | — | — | US | disclosed |
| US-5962423-A | Treatment of bacterial dysentery | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 1999-10-05 | — | — | US | disclosed |