Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | LIPA | P38571 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1552476 | 0.96 | MAPT (0.51) | MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2 | |
| SCHEMBL1552186 | 0.96 | MAPT (0.51) | MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2 | |
| SCHEMBL80230 | 0.96 | MAPT (0.51) | MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2 | |
| SCHEMBL12158782 | 0.90 | MAPT (0.47) | MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2 | |
| SCHEMBL29443775 | 0.85 | LIPA (0.46) | MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2 | |
| SCHEMBL15187643 | 0.84 | MAPT (0.41) | MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2 | |
| SCHEMBL17269271 | 0.83 | MAPT (0.40) | MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2 | |
| SCHEMBL28199763 | 0.83 | MAPT (0.51) | MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2 | |
| SCHEMBL22733771 | 0.81 | MAPT (0.53) | MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2 | |
| SCHEMBL113594 | 0.81 | APOBEC3A (0.39) | MAPTAPOBEC3AAPOBEC3GHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105283531-B | Detergent composition | 狮王株式会社 | 2018-11-02 | — | — | CN | disclosed |
| CN-104918603-A | Anti-aging skin external composition and preparation method thereof | HAYASHIBARA CO | 2015-09-16 | — | — | CN | disclosed |
| EP-1123376-A2 | LAUNDRY AND CLEANING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2001-08-16 | — | — | EP | disclosed |
| WO-2000002982-A2 | LAUNDRY AND CLEANING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2000-01-20 | — | — | WO | disclosed |