Sugi Predict

Sugi Predict / Compounds / SCHEMBL7873016

SCHEMBL7873016

SCHEMBL7873016

CC1(C)CCC(C)(C)c2cc(-c3cc(-c4ccc(C(=O)O)cc4)ccc3-c3ccccc3)ccc21.CC1(C)CCC(C)(C)c2cc(-c3cc(-c4ccc(C(=O)O)cc4)ccc3-c3ccccc3)ccc21

nearest known ligand 0.83

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ RARB P10826 16/20 0.83
▸ RARG P13631 15/20 0.83
▸ RXRA P19793 5/20 0.83
▸ RARA P10276 13/20 0.76
▸ RXRB P28702 2/20 0.56
▸ RXRG P48443 2/20 0.56
▸ ABCB1 P08183 1/20 0.54
▸ ABCC1 P33527 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5846429 1.00 RARB (0.83) RARBRARGRXRARARARXRB
SCHEMBL5846624 1.00 RARB (0.83) RARBRARGRXRARARARXRB
SCHEMBL5846034 0.97 RARB (0.82) RARBRARGRXRARARARXRB
SCHEMBL2917374 0.91 RARB (0.76) RARBRARGRXRARARARXRB
SCHEMBL5847073 0.91 RARB (0.73) RARBRARGRXRARARARXRB
SCHEMBL5846789 0.90 RARG (0.67) RARBRARGRXRARARARXRB
SCHEMBL5847632 0.90 RARB (0.67) RARBRARGRXRARARARXRB
SCHEMBL5845438 0.90 RARG (0.75) RARBRARGRXRARARARXRB
SCHEMBL5846039 0.89 RARG (0.75) RARBRARGRXRARARARXRB
SCHEMBL5846360 0.88 RARB (0.65) RARBRARGRXRARARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6316009-B1 FOR THERAPY OF DERMATOLOGICAL COMPLAINTS ASSOCIATED WITH A KERATINIZATION DISORDER, AND FOR COMBATING AGEING OF THE SKIN GALDERMA RESEARCH & DEVELOPMENT (FR) 2001-11-13 — — US claimed