SCHEMBL7873065

SCHEMBL7873065

CCc1nccc(-c2ccc(C(=O)OC)c(F)c2)c1-c1ccc(N)nc1

nearest known ligand 0.58

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MTOR P42345 20/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7880600 0.89 MTOR (0.54) MTOR
SCHEMBL7880093 0.88 MTOR (0.54) MTOR
SCHEMBL7881625 0.88 MTOR (0.52) MTOR
SCHEMBL7875765 0.88 MTOR (0.56) MTOR
SCHEMBL7883941 0.88 MTOR (0.50) MTOR
SCHEMBL12772974 0.87 MTOR (0.53) MTOR
SCHEMBL12773685 0.87 MTOR (0.73) MTOR
SCHEMBL7879088 0.84 MTOR (0.75) MTOR
SCHEMBL6892332 0.84 PIK3CA (0.59) MTOR
SCHEMBL693916 0.84 MTOR (0.80) MTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010122069-A1 5-ALKYNYL-PYRIDINES BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2010-10-28 WO disclosed