⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL995994 | 0.69 | — | — | |
| SCHEMBL1525991 | 0.69 | — | — | |
| SCHEMBL329239 | 0.67 | — | — | |
| SCHEMBL3511118 | 0.65 | — | — | |
| SCHEMBL5321527 | 0.65 | — | — | |
| SCHEMBL10705832 | 0.65 | — | — | |
| SCHEMBL5321523 | 0.65 | — | — | |
| SCHEMBL3079990 | 0.62 | — | — | |
| SCHEMBL4165616 | 0.62 | — | — | |
| SCHEMBL3082972 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37438-E1 | Acetamidine derivatives and their use as inhibitors for the nitric oxide synthase | GLAXO WELLCOME INC. | 2001-11-06 | — | — | US | disclosed |
| US-6265519-B1 | CURING AN EPOXIDE | MOLEX INCORPORATED | 2001-07-24 | — | — | US | disclosed |
| US-5866612-A | Acetamidine derivatives and their use as inhibitors for the nitric oxide synthase | GLAXO WELLCOME INC. (US) | 1999-02-02 | — | — | US | disclosed |
| EP-0799191-A1 | ACETAMIDINE DERIVATIVES AND THEIR USE AS INHIBITORS FOR THE NITRIC OXIDE SYNTHASE | THE WELLCOME FOUNDATION LIMITED (GB) | 1997-10-08 | — | — | EP | disclosed |
| WO-1996019440-A1 | ACETAMIDINE DERIVATIVES AND THEIR USE AS INHIBITORS FOR THE NITRIC OXIDE SYNTHASE | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-06-27 | — | — | WO | disclosed |
| EP-0108633-B1 | ASSAY FOR QUALITATIVELY AND/OR QUANTITATIVELY MEASURING HLH OR HCG IN BODY FLUIDS AND REAGENTS THEREFOR | CORNELL RESEARCH FOUNDATION, INC. (US) | 1991-02-13 | — | — | EP | disclosed |
| US-4880914-A | COMMON RECEPTOR FOR BOTH HORMONES | CORNELL RESEARCH FOUNDATION, INC. | 1989-11-14 | — | — | US | disclosed |
| US-4560649-A | COMPLEXING WITH DISULFIDE COMPOUND | CORNELL RESEARCH FOUNDATION (US) | 1985-12-24 | — | — | US | disclosed |
| EP-0108633-A2 | Assay for qualitatively and/or quantitatively measuring hLH or hCG in body fluids and reagents therefor | CORNELL RESEARCH FOUNDATION, INC. (US) | 1984-05-16 | — | — | EP | disclosed |