Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL505113 | 0.92 | GRM5 (0.56) | GRM5KCNH2 | |
| SCHEMBL10250748 | 0.89 | GRM5 (0.45) | GRM5KCNH2 | |
| SCHEMBL505079 | 0.86 | GRM5 (0.57) | GRM5KCNH2 | |
| SCHEMBL505510 | 0.84 | GRM5 (0.54) | GRM5KCNH2 | |
| SCHEMBL10250213 | 0.84 | GRM5 (0.44) | GRM5KCNH2 | |
| SCHEMBL10250319 | 0.83 | GRM5 (0.47) | GRM5KCNH2 | |
| SCHEMBL10250755 | 0.81 | GRM5 (0.43) | GRM5KCNH2 | |
| SCHEMBL506158 | 0.80 | GRM5 (0.61) | GRM5 | |
| SCHEMBL505123 | 0.80 | GRM5 (0.47) | GRM5KCNH2 | |
| SCHEMBL505150 | 0.79 | GRM5 (0.49) | GRM5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010114971-A1 | COMPOUNDS FOR TREATING DISORDERS MEDIATED BY METABOTROPIC GLUTAMATE RECEPTOR 5, AND METHODS OF USE THEREOF | SEPRACOR INC. (US) | 2010-10-07 | — | — | WO | disclosed |