Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | FLT3 | P36888 | 3/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7882019 | 0.92 | MEN1 (0.48) | MEN1KMT2ARXFP1FLT3PDGFRB | |
| SCHEMBL7884905 | 0.89 | MEN1 (0.47) | MEN1KMT2ARXFP1FLT3PDGFRB | |
| SCHEMBL7873705 | 0.88 | MEN1 (0.46) | MEN1KMT2ARXFP1FLT3PDGFRB | |
| SCHEMBL7882345 | 0.86 | MEN1 (0.48) | MEN1KMT2ARXFP1FLT3PDGFRB | |
| SCHEMBL7885051 | 0.85 | MEN1 (0.34) | MEN1KMT2ARXFP1FLT3ACHE | |
| SCHEMBL7881845 | 0.83 | MAOB (0.36) | MEN1KMT2ARXFP1ACHEMAOB | |
| SCHEMBL7879925 | 0.82 | FLT3 (0.50) | MEN1KMT2ARXFP1FLT3PDGFRB | |
| Hydrochloric Acid SCHEMBL7877487 | 0.82 | FLT3 (0.58) | MEN1KMT2ARXFP1FLT3PDGFRB | |
| SCHEMBL7873235 | 0.82 | FLT3 (0.47) | MEN1KMT2ARXFP1FLT3PDGFRB | |
| SCHEMBL7884458 | 0.81 | MAPT (0.39) | MEN1KMT2AFLT3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248772-B1 | HYPOTENSIVE AGENTS; ANTIARRHYTHMIA AGENTS; ANTIDIABETIC AGENTS; ANTIPROLIFERATIVE AGENTS | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 2001-06-19 | — | — | US | disclosed |
| US-6169107-B1 | USEFUL FOR THE TREATMENT AND PREVENTION OF DISEASES CAUSED BY INCREASED SODIUM/PROTON (NA.SUP.+ /H.SUP.+) EXCHANGER ACTIVITY, FOR EXAMPLE, HYPERTENSION, ARRHYTHMIA, ANGINA PECTORIS, CARDIAC HYPERTROPHY, DIABETES MELLITUS | SUMITOMO PHARMACEUTICAL CO., LTD. (JP) | 2001-01-02 | — | — | US | disclosed |
| EP-0708091-A2 | Indoloylguanidine derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-04-24 | — | — | EP | disclosed |