Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1664256 | 0.82 | HCAR2 (0.40) | POLBCTDSP1TDP1HCAR2NAAA | |
| SCHEMBL9179049 | 0.81 | HCAR2 (0.44) | HCAR2NAAAALDH1A1S1PR5S1PR1 | |
| SCHEMBL1664255 | 0.79 | HCAR2 (0.40) | POLBHCAR2NAAAALDH1A1TP53 | |
| SCHEMBL16866269 | 0.79 | POLB (0.62) | POLBALDH1A1PPARGKMT2AMEN1 | |
| SCHEMBL21120133 | 0.79 | POLB (0.62) | POLBALDH1A1PPARGKMT2AMEN1 | |
| SCHEMBL15590173 | 0.79 | POLB (0.62) | POLBALDH1A1PPARGKMT2AMEN1 | |
| SCHEMBL16866285 | 0.79 | POLB (0.62) | POLBALDH1A1PPARGKMT2AMEN1 | |
| SCHEMBL18674042 | 0.79 | POLB (0.62) | POLBALDH1A1PPARGKMT2AMEN1 | |
| SCHEMBL16866286 | 0.79 | POLB (0.62) | POLBALDH1A1PPARGKMT2AMEN1 | |
| SCHEMBL18674046 | 0.79 | POLB (0.62) | POLBALDH1A1PPARGKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313095-B1 | HERPES VIRAL RIBONUCLEOTIDE REDUCTASE INHIBITORS | BOEHRINGER INGELHEIM (CANADA), LTD. (CA) | 2001-11-06 | — | — | US | disclosed |
| EP-0411333-B1 | Antiherpes tetrapeptide derivatives having a substituted aspartic acid side chain | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1995-05-31 | — | — | EP | disclosed |
| EP-0411333-A1 | Antiherpes tetrapeptide derivatives having a substituted aspartic acid side chain | BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) | 1991-02-06 | — | — | EP | disclosed |