⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17816366 | 1.00 | — | — | |
| SCHEMBL10067006 | 0.79 | — | — | |
| SCHEMBL11125110 | 0.77 | — | — | |
| SCHEMBL4048543 | 0.76 | — | — | |
| SCHEMBL13922054 | 0.76 | — | — | |
| SCHEMBL1392324 | 0.74 | — | — | |
| SCHEMBL10918298 | 0.74 | — | — | |
| SCHEMBL13412034 | 0.74 | — | — | |
| SCHEMBL10067007 | 0.73 | MPI (0.32) | — | |
| SCHEMBL10067041 | 0.73 | MPI (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9861652-B2 | 2′ Fluoronucleosides | EMORY UNIVERSITY (US) | 2018-01-09 | — | — | US | disclosed |
| US-20160158266-A1 | 2' FLUORONUCLEOSIDES | EMORY UNIVERSITY | 2016-06-09 | — | — | US | disclosed |
| US-9180138-B2 | 2′-fluoronucleosides | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2015-11-10 | — | — | US | disclosed |
| US-9180138-B2 | 2′-fluoronucleosides | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2015-11-10 | — | — | US | disclosed |
| US-20130157971-A1 | 2'-FLUORONUCLEOSIDES | SCHINAZI RAYMOND F (US) | 2013-06-20 | — | — | US | disclosed |
| US-20130157971-A1 | 2'-FLUORONUCLEOSIDES | SCHINAZI RAYMOND F (US) | 2013-06-20 | — | — | US | disclosed |
| US-8168583-B2 | 2-fluoronucleosides | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-05-01 | — | — | US | disclosed |
| US-8168583-B2 | 2-fluoronucleosides | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-05-01 | — | — | US | disclosed |
| US-20100173863-A1 | 2-Fluoronucleosides | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-07-08 | — | — | US | disclosed |
| US-20100173863-A1 | 2-Fluoronucleosides | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-07-08 | — | — | US | disclosed |
| US-RE37449-E1 | INCLUDING 1,4-REDUCTION OF DIMERIC IMINIUM INTERMEDIATE TO AN ENAMINE BY REACTION WITH A 1,4-DIHYDROPYRIDINE; OXIDATIVE TRANSFORMATION OF THE PRODUCT TO A SECOND IMINIUM INTERMEDIATE; REDUCTION OF THE SECOND INTERMEDIATE | UNIVERSITY OF BRITISH COLUMBIA (CA) | 2001-11-13 | — | — | US | disclosed |
| US-5756531-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | ABBOTT LABORATORIES (US) | 1998-05-26 | — | — | US | disclosed |
| WO-1997041100-A1 | IMINOXY DERIVATIVES OF INDOLE AND INDENE COMPOUNDS AS INHIBITORS OF PROSTAGLANDIN BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1997-11-06 | — | — | WO | disclosed |
| EP-0403909-B1 | Method for the production of 2,3-dialkoxypropanals | BASF AG (DE) | 1994-04-06 | — | — | EP | disclosed |
| US-5081313-A | PROCESS FOR THE PREPARATION OF 2,3-DIALKOXYPROPANALS | BASF AKTIENGESELLSCHAFT (DE) | 1992-01-14 | — | — | US | disclosed |
| US-5047528-A | Antiviral, Antitumor And Antileukemic Agents | UNIVERSITY OF BRISTISH COLUMBIA (CA) | 1991-09-10 | — | — | US | disclosed |
| EP-0403909-A2 | Method for the production of 2,3-dialkoxypropanals | BASF Aktiengesellschaft (DE) | 1990-12-27 | — | — | EP | disclosed |
| US-4013632-A | SYNTHETIC FIBERS | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1977-03-22 | — | — | US | disclosed |