SCHEMBL78743

SCHEMBL78743

O=[N+]([O-])c1ccccc1Cl

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.62
MAPK1 P28482 3/20 0.56
TSHR P16473 2/20 0.56
HSD17B10 Q99714 1/20 0.54
ALDH1A1 P00352 4/20 0.54
MAPT P10636 2/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
TDP1 Q9NUW8 4/20 0.52
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
VCAM1 P19320 2/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
GPR35 Q9HC97 1/20 0.50
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
CYP2C19 P33261 1/20 0.49
LMNA P02545 1/20 0.49
HTT P42858 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27873887 1.00 HPGD (0.62) HPGDMAPK1TSHRHSD17B10ALDH1A1
SCHEMBL29962795 1.00 HPGD (0.62) HPGDMAPK1TSHRHSD17B10ALDH1A1
Hydrochloric Acid SCHEMBL28518250 0.98 HPGD (0.60) HPGDMAPK1TSHRHSD17B10ALDH1A1
Selenium SCHEMBL10603347 0.98 HPGD (0.60) HPGDMAPK1TSHRHSD17B10ALDH1A1
Fluoride SCHEMBL3957041 0.98 HPGD (0.60) HPGDMAPK1TSHRHSD17B10ALDH1A1
SCHEMBL14855732 0.98 HPGD (0.60) HPGDMAPK1TSHRHSD17B10ALDH1A1
Fluoride SCHEMBL3957036 0.98 HPGD (0.60) HPGDMAPK1TSHRHSD17B10ALDH1A1
1,2-Dichlorobenzene SCHEMBL11313909 0.98 HPGD (0.60) HPGDMAPK1TSHRHSD17B10ALDH1A1
SCHEMBL14855734 0.98 HPGD (0.60) HPGDMAPK1TSHRHSD17B10ALDH1A1
Fluoride SCHEMBL27336627 0.98 HPGD (0.60) HPGDMAPK1TSHRHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9890 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070479-A Ultrasonic indicating device and method for monitoring ultrasonic treatment JP实验室股份有限公司 2026-05-19 CN claimed
CN-121574076-A Environment-friendly sulfonamide amidation preparation method 山东大斯夫材料科技有限公司 2026-02-27 CN claimed
CN-119798054-B Alkyl functionalized cyclo-resveratrol hydrocarbon, preparation method thereof, capillary gas chromatographic column and application 洛阳师范学院 2025-06-13 CN claimed
CN-120136706-A Method for preparing nitroaniline by ammonolysis of meta-position oil based on micro-flow field reaction technology 南京工业大学 2025-06-13 CN claimed
WO-2025120375-A1 A PROCESS FOR THE PREPARATION OF HERBICIDE INTERMEDIATES GHARDA CHEMICALS LIMITED (IN) 2025-06-12 WO claimed
CN-120117989-A One-pot synthesis method of fluxapyroxad intermediate 3',4',5' -trifluoro-2-nitrobiphenyl 辽宁众辉生物科技有限公司 2025-06-10 CN claimed
CN-120082286-A High-stain-resistance hot-melt marking material and preparation method thereof 朝阳路源交通科技有限公司 2025-06-03 CN claimed
CN-120058529-A Method for removing organic chlorine by catalytic hydrogenation 中国石油化工股份有限公司 2025-05-30 CN claimed
EP-4549619-A1 PREPARATION OF AMINES BY HYDROGENATION OF NITRO COMPOUNDS USING HYDROGEN WITH LOW DEUTERIUM CONTENT BASF SE (DE) 2025-05-07 EP claimed
CN-119874621-A Pharmaceutical composition containing pyrazole ether compound and application thereof 上海晓明检测技术服务有限公司 2025-04-25 CN claimed
US-4107220-A Gas phase nitration of chlorobenzene MONSANTO COMPANY (US) 1978-08-15 US claimed
US-4102753-A LOWER ALKYLENE GLYCOL, LOWER OXYALKYLENE GLYCOL, OR GLYCEROL PPG INDUSTRIES, INC. (US) 1978-07-25 US claimed
US-4070401-A HYDROGENATION, DEHALOGENATION INHIBITOR MITSUI TOATSU CHEMICALS INC. (JA) 1978-01-24 US claimed
US-4069262-A Preparation of 2-fluoronitrobenzene E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-01-17 US claimed
US-4020107-A ACIDIC PHOSPHORUS COMPOUND DEHALOGENATION INHIBITOR E. I. DU PONT DE NEMOURS AND CO. (US) 1977-04-26 US claimed
US-3982958-A HERMETICALLY SEALED UNION CARBIDE CORPORATION (US) 1976-09-28 US claimed
US-3980581-A NUCLEATING AGENTS, SOLID SOLUTIONS BIO-MEDICAL SCIENCES, INC. (US) 1976-09-14 US claimed
US-3956153-A MINIMIZATION OF UNDERCOOLING BIO-MEDICAL SCIENCES, INC. (US) 1976-05-11 US claimed
US-3946612-A Temperature indicating compositions BIO-MEDICAL SCIENCES, INC. (US) 1976-03-30 US claimed
US-3931321-A Process for the preparation of O-aminothiophenols HOECHST AKTIENGESELLSCHAFT (DT) 1976-01-06 US claimed