Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2024724 | 0.87 | BACE1 (0.51) | BACE1 | |
| SCHEMBL2028914 | 0.87 | BACE1 (0.56) | BACE1 | |
| SCHEMBL2255225 | 0.87 | BACE1 (0.56) | BACE1 | |
| SCHEMBL2026159 | 0.86 | BACE1 (0.55) | BACE1 | |
| SCHEMBL12578623 | 0.86 | BACE1 (0.50) | BACE1 | |
| SCHEMBL12578536 | 0.85 | BACE1 (0.55) | BACE1 | |
| SCHEMBL2025473 | 0.84 | BACE1 (0.54) | BACE1 | |
| SCHEMBL2027404 | 0.84 | BACE1 (0.59) | BACE1 | |
| SCHEMBL2026818 | 0.84 | BACE1 (0.68) | BACE1 | |
| SCHEMBL7875153 | 0.81 | BACE1 (0.45) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010107384-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-09-23 | — | — | WO | disclosed |
| WO-2010042030-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-04-15 | — | — | WO | disclosed |