Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.49 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.46 |
| ▸ | CTSD | P07339 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7874432 | 0.86 | BACE1 (0.43) | BACE1CTSD | |
| SCHEMBL7875991 | 0.85 | BACE1 (0.66) | BACE1BACE2CTSDAPP | |
| SCHEMBL7876047 | 0.82 | BACE1 (0.51) | BACE1BACE2CTSDAPP | |
| SCHEMBL7876045 | 0.82 | BACE1 (0.48) | BACE1BACE2CTSDAPP | |
| SCHEMBL7875849 | 0.81 | BACE1 (0.42) | BACE1BACE2CTSDAPP | |
| SCHEMBL7874435 | 0.81 | BACE1 (0.57) | BACE1BACE2CTSDAPP | |
| SCHEMBL7874460 | 0.80 | BACE1 (0.66) | BACE1 | |
| SCHEMBL7869235 | 0.80 | BACE1 (0.69) | BACE1BACE2 | |
| SCHEMBL7880655 | 0.79 | BACE1 (0.62) | BACE1BACE2CTSDAPP | |
| SCHEMBL7872319 | 0.74 | BACE1 (0.49) | BACE1BACE2CTSDAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010107384-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-09-23 | — | — | WO | disclosed |