Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7876138 | 1.00 | CYP3A4 (0.33) | CYP3A4CYP2D6PTPN11SOAT1 | |
| SCHEMBL7876135 | 1.00 | CYP3A4 (0.33) | CYP3A4CYP2D6PTPN11SOAT1 | |
| SCHEMBL7871760 | 0.90 | CYP3A4 (0.39) | CYP3A4CYP2D6PTPN11SOAT1 | |
| SCHEMBL7877662 | 0.90 | CYP3A4 (0.39) | CYP3A4CYP2D6PTPN11SOAT1 | |
| SCHEMBL7875959 | 0.89 | CYP3A4 (0.39) | CYP3A4CYP2D6PTPN11SOAT1 | |
| SCHEMBL7879454 | 0.88 | CYP3A4 (0.38) | CYP3A4CYP2D6PTPN11SOAT1 | |
| SCHEMBL9562059 | 0.81 | RARB (0.39) | — | |
| SCHEMBL9122773 | 0.81 | RARB (0.39) | — | |
| SCHEMBL9562056 | 0.81 | RARB (0.39) | — | |
| SCHEMBL8992363 | 0.81 | RARB (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883618-B1 | DIFLUOROPHENYL PYRIMIDYL PYRIDINE DERIVATIVES AND THE USE THEREOF IN LIQUID CRYSTAL MIXTURES | AVENTIS RES & TECH GMBH & CO (DE) | 2001-05-16 | — | — | EP | disclosed |
| US-6022492-A | FOR FERROELECTRIC SWITCHING AND/OR DISPLAY DEVICE | HOESCHT RESEARCH & TECHNOLOGY DEUTCHLAND GMBH & CO. (DE) | 2000-02-08 | — | — | US | disclosed |
| EP-0883618-A1 | DIFLUOROPHENYL PYRIMIDYL PYRIDINE DERIVATIVES AND THE USE THEREOF IN LIQUID CRYSTAL MIXTURES | Hoechst Research & Technology Deutschland GmbH & Co. KG (DE) | 1998-12-16 | — | — | EP | disclosed |
| WO-1997024351-A1 | DIFLUOROPHENYL PYRIMIDYL PYRIDINE DERIVATIVES AND THE USE THEREOF IN LIQUID CRYSTAL MIXTURES | HOECHST RESEARCH & TECHNOLOGY DEUTSCHLAND GMBH & CO.KG (DE) | 1997-07-10 | — | — | WO | disclosed |