Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 4/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7887552 | 1.00 | ANPEP (0.40) | ANPEPGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30308811 | 1.00 | ANPEP (0.40) | ANPEPGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8382393 | 1.00 | ANPEP (0.40) | ANPEPGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL15848481 | 0.79 | SLC18A3 (0.46) | ANPEP | |
| SCHEMBL270201 | 0.79 | KDM1A (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL7174206 | 0.77 | GRIN2D (0.42) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL7178967 | 0.77 | GRIN2D (0.42) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL3867845 | 0.77 | ANPEP (0.42) | ANPEPGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5271544 | 0.77 | ANPEP (0.42) | ANPEPGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL783223 | 0.77 | ANPEP (0.42) | ANPEPGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6171832-B1 | FERMENTING STARTING MATERIAL IN CULTURE, RECOVERING PRODUCT; BY PRODUCT INHIBITION; CHEMICAL INTERMEDIATE FOR SYNTHESIS OF INDINAVIR, A POTENT HUMAN IMMUNODEFICIENCY VIRUS PROTEASE INHIBITOR | MERCK & CO., INC. | 2001-01-09 | — | — | US | disclosed |
| US-5824540-A | CULTURE FOR CONVERSION OF INDENE TO AMINO INDNOL | MERCK & CO., INC. (US) | 1998-10-20 | — | — | US | disclosed |
| US-5605819-A | USING BROMIDE ION AND HYDROGEN PEROXIDE | MERCK & CO., INC. (US) | 1997-02-25 | — | — | US | disclosed |