Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 6/20 | 0.52 |
| ▸ | RARB | P10826 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | RARG | P13631 | 4/20 | 0.52 |
| ▸ | RARA | P10276 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | BLVRB | P30043 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 13/20 | 0.46 |
| ▸ | RXRB | P28702 | 9/20 | 0.46 |
| ▸ | RXRG | P48443 | 8/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773634 | 0.93 | CYP26A1 (0.50) | CYP26A1RARBCYP3A4RARGRARA | |
| SCHEMBL7881530 | 0.92 | CYP26A1 (0.49) | CYP26A1RARBCYP3A4RARGRARA | |
| SCHEMBL7876910 | 0.88 | CYP26A1 (0.53) | CYP26A1RARBCYP3A4RARGRARA | |
| SCHEMBL7881552 | 0.88 | CYP26A1 (0.52) | CYP26A1RARBCYP3A4RARGRARA | |
| SCHEMBL7876767 | 0.88 | CYP26A1 (0.52) | CYP26A1RARBCYP3A4RARGRARA | |
| SCHEMBL7876904 | 0.88 | CYP26A1 (0.52) | CYP26A1RARBCYP3A4RARGRARA | |
| SCHEMBL7876757 | 0.88 | CYP26A1 (0.52) | CYP26A1RARBCYP3A4RARGRARA | |
| SCHEMBL7883300 | 0.88 | CYP26A1 (0.52) | CYP26A1RARBCYP3A4RARGRARA | |
| SCHEMBL7876888 | 0.88 | CYP26A1 (0.52) | CYP26A1RARBCYP3A4RARGRARA | |
| SCHEMBL8346566 | 0.86 | PLK1 (0.42) | CYP26A1RARBCYP3A4RARGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6171603-B1 | TREATING SKIN, HAIR, CARDIOVASCULAR, AUTOIMMUNE AND VISION DISORDERS; ADMINISTERING AS ANTICARCINOGENIC, ANTIDEPRESSANT,ANTIINFLAMMATORY, AND ANTIACNE AGENTS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (FR) | 2001-01-09 | — | — | US | disclosed |