⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL787693 | 0.84 | — | — | |
| SCHEMBL385678 | 0.80 | TSHR (0.36) | — | |
| SCHEMBL11149019 | 0.74 | — | — | |
| Butane SCHEMBL9770092 | 0.72 | — | — | |
| SCHEMBL4709957 | 0.71 | — | — | |
| SCHEMBL5992680 | 0.70 | — | — | |
| Bicarbonate SCHEMBL10931175 | 0.68 | TSHR (0.33) | — | |
| SCHEMBL8718780 | 0.67 | — | — | |
| SCHEMBL6296953 | 0.67 | — | — | |
| SCHEMBL8846747 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3377473-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2024-06-19 | — | — | EP | disclosed |
| US-20240132470-A1 | Antibacterial Compounds | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2024-04-25 | — | — | US | disclosed |
| EP-4302830-A2 | QUINAZOLINE DERIVATIVES USED TO TREAT HIV | Gilead Sciences, Inc. (US) | 2024-01-10 | — | — | EP | disclosed |
| US-11866419-B2 | Antibacterial compounds | Janssen Sciences Ireland Unlimited Company (IE) | 2024-01-09 | — | — | US | disclosed |
| EP-3960735-B1 | QUINAZOLINE DERIVATIVES USED TO TREAT HIV | GILEAD SCIENCES INC (US) | 2023-09-13 | — | — | EP | disclosed |
| US-20230133817-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2023-05-04 | — | — | US | disclosed |
| US-20230043136-A1 | Quinazoline Compounds | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE AS CR, V.V.I. (CZ) | 2023-02-09 | — | — | US | disclosed |
| US-20230014173-A1 | Antibacterial Compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2023-01-19 | — | — | US | disclosed |
| US-20220378675-A1 | COMPOUNDS REDUCING MALODOUR PERCEPTION AND THE USE THEREOF | CHEMCOM S.A. (BE) | 2022-12-01 | — | — | US | disclosed |
| EP-4074378-A1 | ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2022-10-19 | — | — | EP | disclosed |
| EP-0037310-B1 | SUBSTITUTED DEOXYADENOSINE DERIVATIVES | MERRELL TORAUDE ET COMPAGNIE (FR) | 1984-05-09 | — | — | EP | disclosed |
| US-4436662-A | SEDATIVES, TRANQUILIZERS | HOFFMANN-LA ROCHE INC. (US) | 1984-03-13 | — | — | US | disclosed |
| US-4431823-A | SEDATIVES | HOFFMANN-LA ROCHE INC. (US) | 1984-02-14 | — | — | US | disclosed |
| US-4428879-A | SEDATIVES, TRANQUILIZERS | HOFFMANN-LA ROCHE INC. (US) | 1984-01-31 | — | — | US | disclosed |
| US-4428878-A | SEDATIVES, TRANQUILIZERS | HOFFMANN-LA ROCHE INC. (US) | 1984-01-31 | — | — | US | disclosed |
| US-4409390-A | 3-(2-AMINOETHYL)-4-(2-HYDROXYBENZYL-PHENYL) PYRROLE INTERMEDIATE | HOFFMANN-LA ROCHE INC. (US) | 1983-10-11 | — | — | US | disclosed |
| US-4405518-A | SEDATIVES | HOFFMANN-LA ROCHE INC. (US) | 1983-09-20 | — | — | US | disclosed |
| US-4379765-A | SEDATIVES, ANXIETY | HOFFMANN-LA ROCHE INC. (US) | 1983-04-12 | — | — | US | disclosed |
| US-4374128-A | TREATING RAPID CELL PROLIFERATION | MERRELL TORAUDE ET COMPAGNIE (FR) | 1983-02-15 | — | — | US | disclosed |
| US-4354973-A | SEDATIVES AND ANXIOLYTICS | HOFFMANN-LA ROCHE INC. (US) | 1982-10-19 | — | — | US | disclosed |